Studies on Analysis of Nitrofuran Derivatives (V)

Metabolism of drugs. LXXX. The metabolic fate of nitrofuran derivatives. 3. Studies on enzymes in small intestinal mucosa of rat catalyzing degradation of nitrofuran derivatives.

The enzymes responsible for the degradation of nitrofuran derivatives in rat small intestinal mucosa were examined in vitro.As a result,it was suggested that the initial reactions in the degradation of 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide(AF-2) and 5-nitro-2-furfural semicarbazone(nitrofurazone)are mainly catalyzed by xanthine oxidase , while that of 2-amino-5-[2-(5-nitro-2-fury1)-1-(2-fur...

analysis of reading comprehension needs of the students of paramedical studies: the case of the students of health information management (him)

چکیده ندارد.

Antifungal activity studies of some mannich bases carrying nitrofuran moiety

A series of 3-substituted-4-(5-nitro-2-furfurylidene)amino-5-mercapto-1,2,4-triazoles 3 and their Mannich bases have been synthesized. The structures of these Schiff bases and Mannich bases were confirmed on the basis of elemental analysis, H NMR and mass spectral data. The above compounds were also screened for their antifungal activity against C.albicans.

Studies on nicotinamide derivatives.

Lipophilicity Studies on Thiosemicarbazide Derivatives.

The lipophilicity of two series of thiosemicarbazide derivatives was assessed by the RP-HPLC method with the RP-18 chromatographic column and the methanol-water mixture as the mobile phase. Distribution coefficients logPHPLC were compared to calculated values generated by commonly used AClogP software and quantum chemical calculations. The reliability of the predictions was evaluated using the ...