Structure of Ddi2, a highly inducible detoxifying metalloenzyme from Saccharomyces cerevisiae
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چکیده
منابع مشابه
Inducible Gene RNR3 in Saccharomyces cerevisiae
Ribonucleotide reductase is an essential enzyme that catalyzes the rate limiting step for production of the deoxyribonucleotides required for DNA synthesis. It is encoded by three genes, RNRI, RNRZ and RNR3, each of which is inducible by agents that damage DNA or block DNA replication. To probe the signaling pathway mediating this DNA damage response, we have designed a general selection system...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2019
ISSN: 0021-9258
DOI: 10.1074/jbc.ra118.006394