Structure of a Bud6/Actin Complex Reveals a Novel WH2-like Actin Monomer Recruitment Motif
نویسندگان
چکیده
منابع مشابه
Structural basis of actin sequestration by thymosin-beta4: implications for WH2 proteins.
The WH2 (Wiscott-Aldridge syndrome protein homology domain 2) repeat is an actin interacting motif found in monomer sequestering and filament assembly proteins. We have stabilized the prototypical WH2 family member, thymosin-beta4 (Tbeta4), with respect to actin, by creating a hybrid between gelsolin domain 1 and the C-terminal half of Tbeta4 (G1-Tbeta4). This hybrid protein sequesters actin mo...
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ژورنال
عنوان ژورنال: Structure
سال: 2015
ISSN: 0969-2126
DOI: 10.1016/j.str.2015.05.015