Structure and protective efficacy of the Staphylococcus aureus autocleaving protease EpiP

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Serine protease EpiP from Staphylococcus epidermidis catalyzes the processing of the epidermin precursor peptide.

The function of serine protease EpiP in epidermin biosynthesis was investigated. Epidermin is synthesized as a 52-amino-acid precursor peptide, EpiA, which is posttranslationally modified and processed to the mature 22-amino-acid peptide antibiotic. epiP was expressed in Staphylococcus carnosus with xylose-regulated expression vector pCX15. The cleavage of the unmodified EpiA precursor peptide ...

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Serine Protease EpiP from Staphylococcus epidermidis Catalyzes the Processing of the Epidermin Precursor Peptide

The function of serine protease EpiP in epidermin biosynthesis was investigated. Epidermin is synthesized as a 52-amino-acid precursor peptide, EpiA, which is posttranslationally modified and processed to the mature 22-amino-acid peptide antibiotic. epiP was expressed in Staphylococcus carnosus with xylose-regulated expression vector pCX15. The cleavage of the unmodified EpiA precursor peptide ...

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Comparison of Efficacy of Two Disinfectants Against Foodborne Staphylococcus aureus

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2014

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fj.13-241737