Structural studies of a new hemoglobin: HbJ Lens, β13(A10) Ala → Asp
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چکیده
منابع مشابه
Hemoglobin Crete ( fi 129 Ala - k Pro ) : A New High - Affinity Variant Interacting With $ # { 176 } -
Hemoglobin Crete, 1 29 (H7) ala -k pro, is #{149} new mutant hemoglobin (Hb) with high oxygen affinity that was discovered in a Greek family in various combinations with #{176}and #{244} ’-thaIassemia. The propositus. who presented an unusual clinical picture of an “overcompenseted” hemolytic state. with erythrocytosis. splenomegaly. abnormal red cell morphology, and marked erythroid hyperplasi...
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Specific ligation states of hemoglobin are, when crystallized, capable of taking on multiple quaternary structures. The relationship between these structures, captured in crystal lattices, and hemoglobin structure in solution remains uncertain. Wide-angle X-ray solution scattering (WAXS) is a sensitive probe of protein structure in solution that can distinguish among similar structures and has ...
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[Hb Burgos (α1 CD64(E13)(Asp→Asn)): a new hemoglobin variant detected during follow-up of diabetic patients].
BACKGROUND AND OBJECTIVE The glycated hemoglobin (HbA1c) test by high performance liquid chromatography is a useful tool for the follow-up of diabetes mellitus patients. Some structural hemoglobin (Hb) variants are known to cause interference in the analytical measurement of HbA1c. PATIENTS AND METHODS In this study, it has been characterized a new Hb variant in 4 patients during their regula...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1981
ISSN: 0014-5793
DOI: 10.1016/0014-5793(81)81234-3