Structural modification of Escherichia coli peptidoglycan induced by bicyclomycin.
نویسندگان
چکیده
منابع مشابه
Morphological changes of Escherichia coli induced by bicyclomycin.
Electron microscopic studies with Escherichia coli revealed that bicyclomycin inhibits septum formation and converts the cells to filamentous forms. The antibiotic induced high undulation and numerous blebs of the outer membrane. Sometimes cytoplasmic contents leaked into the lumen of the bleb through a disrupted region of the membrane. Breakage of the outer membrane or blebs led to cell lysis....
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Reaction of 5S RNA with chlorocetaldehyde leads to the conversion of unpaired adenines to the fluorescent 1,N6-etheno-adenine derivatives. Up to 16 of the 23 adenines in free 5S RNA can be modified, the fastest reacting are A29, A34, A57-59. Partial modification of adenines in this area results in a 20% reduction in the efficiency of 5S RNA incorporation into 50S subunits during reconstitution ...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1986
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.39.914