Structural designs that required thinking

Thinking Required

There exists a theory of a single general-purpose learning algorithm which could explain the principles its operation. It assumes the initial rough architecture, a small library of simple innate circuits which are prewired at birth. and proposes that all significant mental algorithms are learned. Given current understanding and observations, this paper reviews and lists the ingredients of such ...

Case Report of Unusual complications after hearing aid fitting that required surgical management

The making of ear mould for hearing aids is generally considered to be a safe process. However, there are a few reported cases of complications caused during mould making. We report the case of a man with 69 years age, where the process of making the mould for a hearing aid led to the perforation of the tympanic membrane and pouring of mould material into the middle ear, necessitating surgical ...

Knowing That I Am Thinking

Soc. ...I speak of what I scarcely understand; but the soul when thinking appears to me to be just talking—asking questions of herself and answering them, affirming and denying. And when she has arrived at a decision, either gradually or by a sudden impulse, and has at last agreed, and does not doubt, this is called her opinion. I say, then, that to form an opinion is to speak, and opinion is a...

What makes a protein a protein? Hydrophobic core designs that specify stability and structural properties.

Here we describe how the systematic redesign of a protein's hydrophobic core alters its structure and stability. We have repacked the hydrophobic core of the four-helix-bundle protein, Rop, with altered packing patterns and various side chain shapes and sizes. Several designs reproduce the structure and native-like properties of the wild-type, while increasing the thermal stability. Other desig...

[Fallacies that have penetrated into scientific thinking].