Structural Brain Network Reorganization in Patients with Neuropsychiatric Systemic Lupus Erythematosus
نویسندگان
چکیده
منابع مشابه
Abnormal brain diffusivity in patients with neuropsychiatric systemic lupus erythematosus.
BACKGROUND AND PURPOSE Neuroimaging techniques have increased our knowledge of the pathogenesis of neuropsychiatric systemic lupus erythematosus (NPSLE) and have been useful in supporting the diagnosis. Nevertheless, new imaging techniques are needed to unravel the exact pathogenesis and to provide diagnostic criteria for NPSLE. In this preliminary study, we investigated whether diffusion-weigh...
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Neuropsychiatric systemic lupus erythematosus (NPSLE) is the least understood, yet perhaps the most prevalent manifestation of lupus. The pathogenesis of NPSLE is multifactorial and involves various inflammatory cytokines, autoantibodies, and immune complexes resulting in vasculopathic, cytotoxic and autoantibody-mediated neuronal injury. The management of NPSLE is multimodal and has not been s...
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Neuropsychiatric (NP) involvement is a prevalent and often severe feature of Systemic Lupus Erythematosus (SLE). Diverse factors are involved in its aetiopathogenesis and treating this condition is often quite challenging. However, clinical trials of biologic therapies in patients with SLE exclude those with severe NP manifestations. The place for the use of biologic approaches is thus even mor...
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ژورنال
عنوان ژورنال: American Journal of Neuroradiology
سال: 2016
ISSN: 0195-6108,1936-959X
DOI: 10.3174/ajnr.a4947