Structural basis of DOTMA for its high intravenous transfection activity in mouse
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چکیده
منابع مشابه
investigating the integration of translation technologies into translation programs in iranian universities: basis for a syllabus design in translation technology
today, information technology and computers are indispensable tools of any profession and translation technologies have become an indispensable part of translator’s workstation. with the increasing demands for high productivity and speed as well as consistency and with the rise of new demands for translation and localization, it is necessary for translators to be familiar with market demands an...
Comparing the Effects of Kaempferol, Galangin and Apigenin Flavanoids on Basis of its Structural Differences in Increasing of Paraoxonase 1 Activity and Attenuating Oxidative Stress Markers in Rats
Background and Aims: Flavonoids as polyphenolic naturally occurring compounds have antioxidant activity. There is increasing evidence suggests that flavonoids may affect the activity of enzymes. Paraoxonase 1 is calcium - dependent enzyme that is present in high density lipoproteins. This enzyme has an important role in the prevention of low density lipoprotein oxidation. We investigated the ef...
متن کاملcomparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.
heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...
15 صفحه اولStructural plasticity of Cid1 provides a basis for its distributive RNA terminal uridylyl transferase activity
Terminal uridylyl transferases (TUTs) are responsible for the post-transcriptional addition of uridyl residues to RNA 3' ends, leading in some cases to altered stability. The Schizosaccharomyces pombe TUT Cid1 is a model enzyme that has been characterized structurally at moderate resolution and provides insights into the larger and more complex mammalian TUTs, ZCCHC6 and ZCCHC11. Here, we repor...
متن کاملStructural Basis for the Antiviral Activity of BST-2/Tetherin and Its Viral Antagonism
The interferon-inducible host restriction factor bone marrow stromal antigen 2 (BST-2/tetherin) blocks the release of HIV-1 and other enveloped viruses. In turn, these viruses have evolved specific antagonists to counteract this host antiviral molecule, such as the HIV-1 protein Vpu. BST-2 is a type II transmembrane protein with an unusual topology consisting of an N-terminal cytoplasmic tail (...
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ژورنال
عنوان ژورنال: Gene Therapy
سال: 2000
ISSN: 0969-7128,1476-5462
DOI: 10.1038/sj.gt.3301153