Structural basis for tRNA modification by Elp3 from Dehalococcoides mccartyi
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منابع مشابه
Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms
The specific aminoacylation of tRNA by tyrosyl-tRNA synthetases (TyrRSs) relies on the identity determinants in the cognate tRNA(Tyr)s. We have determined the crystal structure of Saccharomyces cerevisiae TyrRS (SceTyrRS) complexed with a Tyr-AMP analog and the native tRNA(Tyr)(GPsiA). Structural information for TyrRS-tRNA(Tyr) complexes is now full-line for three kingdoms. Because the archaeal...
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Wybutosine (yW), one of the most complicated modified nucleosides, is found in the anticodon loop of eukaryotic phenylalanine tRNA. This hypermodified nucleoside ensures correct codon recognition by stabilizing codon-anticodon pairings during the decoding process in the ribosome. TYW4 is an S-adenosylmethionine (SAM)-dependent enzyme that catalyzes the final step of yW biosynthesis, methylation...
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ژورنال
عنوان ژورنال: Nature Structural & Molecular Biology
سال: 2016
ISSN: 1545-9993,1545-9985
DOI: 10.1038/nsmb.3265