Structural and mechanistic insights into polymyxin resistance mediated by EptC originating from Escherichia coli
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چکیده
منابع مشابه
Structural and mechanistic insights into cGMP signaling
Background The second messenger cGMP plays a central role in regulating bodily functions, e.g. in the cardiovascular and nervous systems. cGMP is formed by guanylyl cyclases (GC), activates target proteins, and is finally hydrolyzed by cyclic nucleotide phosphodiesterases (PDE). PDEs and GCs are widely used as drug targets, spurring interest in mechanistic and structural insights into their reg...
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ژورنال
عنوان ژورنال: The FEBS Journal
سال: 2018
ISSN: 1742-464X,1742-4658
DOI: 10.1111/febs.14719