Stroke risk factors prepare rat brainstem tissues for modified local Shwartzman reaction.
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چکیده
منابع مشابه
Stroke risk factors prepare rat brainstem tissues for modified local Shwartzman reaction.
Stroke risk factors such as hypertension, diabetes, advanced age, and genetic predisposition to stroke were demonstrated to prepare rat brainstem tissues for a modified local Shwartzman reaction. A single intracisternal injection of endotoxin provoked the reaction, and affected rats manifested neurologic deficits accompanied by pathologic lesions. Brainstem infarcts developed in only a small pr...
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The local Shwartzman reaction was provoked in the skin of the ear, hind leg, and costovertebral angle of the rabbit, as well as in the ventral abdominal skin. Certain adrenergic blocking drugs reduced the incidence of positive reactions when given prior to the provocative dose of bacterial polysaccharide. Epinephrine and other vasoconstrictor drugs administered intradermally into the prepared s...
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متن کاملShwartzman reaction in germfree rabbits.
The local Shwartzman reaction occurred in germfree rabbits which had no natural antibody to endotoxin and none or only a very small amount of immunoglobulin G. From the results it was concluded that the presence of natural antibody to endotoxin is not a prerequisite of the production of the local Shwartzman reaction by bacterial endotoxin.
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ژورنال
عنوان ژورنال: Stroke
سال: 1988
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.19.7.863