Striatal Cholinergic Interneurons Are a Novel Target of Corticotropin Releasing Factor
نویسندگان
چکیده
منابع مشابه
Corticotropin Releasing Factor-Induced CREB Activation in Striatal Neurons Occurs via a Novel Gβγ Signaling Pathway
The peptide corticotropin-releasing factor (CRF) was initially identified as a critical component of the stress response. CRF exerts its cellular effects by binding to one of two cognate G-protein coupled receptors (GPCRs), CRF receptor 1 (CRFR1) or 2 (CRFR2). While these GPCRs were originally characterized as being coupled to Gα(s), leading to downstream activation of adenylyl cyclase (AC) and...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2019
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.0479-19.2019