Stress of Strains: Inbred Mice in Liver Research
نویسندگان
چکیده
منابع مشابه
Liver Oxidative Stress after Renal Ischemia-Reperfusion Injury is Leukocyte Dependent in Inbred Mice
Objective(s) There are some reports in recent years indicating that renal ischemia - reperfusion (IR) induces deleterious changes in remote organs such as liver. The aim of this study was to investigate whether leukocytes have a role on the induction of oxidative stress in liver after renal IR. Materials and Methods Inbred mice in IR donor group were subjected to renal IR injury. In sham don...
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presence of anti5 integrin antibodies, suggesting an action through similar regulatory pathways. Although the drug rapidly reduced ERK phosphorylation, it had little effect on the expression of ERK-1 or ERK-2 proteins. These data suggest that the regulation of Cx expression, and thus of GJ intercellular communication in AECs is exerted through integrin-mediated cell-ECM interactions at the plas...
متن کاملliver oxidative stress after renal ischemia-reperfusion injury is leukocyte dependent in inbred mice
objective(s) there are some reports in recent years indicating that renal ischemia - reperfusion (ir) induces deleterious changes in remote organs such as liver. the aim of this study was to investigate whether leukocytes have a role on the induction of oxidative stress in liver after renal ir. materials and methods inbred mice in ir donor group were subjected to renal ir injury. in sham donor ...
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To identify genetic and environmental factors contributing to the pathogenesis of non-alcoholic fatty liver disease, we examined liver steatosis and related clinical and molecular traits in more than 100 unique inbred mouse strains, which were fed a diet rich in fat and carbohydrates. A >30-fold variation in hepatic TG accumulation was observed among the strains. Genome-wide association stud...
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A BEHAVIORAL COMPARISON OF FOUR INBRED STRAINS OF MICE
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ژورنال
عنوان ژورنال: Gene Expression
سال: 2019
ISSN: 1052-2166
DOI: 10.3727/105221618x15337408678723