منابع مشابه
Stratum corneum dysfunction in dandruff
Dandruff is characterized by a flaky, pruritic scalp and affects up to half the world's population post-puberty. The aetiology of dandruff is multifactorial, influenced by Malassezia, sebum production and individual susceptibility. The commensal yeast Malassezia is a strong contributory factor to dandruff formation, but the presence of Malassezia on healthy scalps indicates that Malassezia alon...
متن کاملDesquamation in the stratum corneum.
To maintain a constant thickness of the stratum corneum the desquamation rate and the de novo production of corneocytes is delicately balanced. Using a plantar stratum corneum model we have obtained evidence that proteolysis is a central event in the desquamation process. A number of regulatory mechanisms for desquamation have been postulated based on our findings.
متن کاملMechanical Properties of the Human Stratum Corneum: Hydration Effects on Graded Delamination of Human Stratum Corneum
Reinhold Dauskardt Stanford University, Professor Materials Sciences and Engineering The stratum corneum (SC) is the outermost layer of the skin. Its process of reneweal is regulated by various mechanisms, including chemical and structural gradients through the SC thickness. In this study, an in vitro mechanics approach for studying the delamination behavior of SC in the direction perpendicular...
متن کاملSkin diseases associated with the depletion of stratum corneum lipids and stratum corneum lipid substitution therapy.
The skin is the largest organ of the body, whose main function is to protect the body against the loss of physiologically important components as well as harmful environmental insults. From the inside to the outside, the skin comprises three major structural layers: the hypodermis, the dermis and the epidermis. The epidermis contains four different sublayers, the stratum corneum (SC), stratum g...
متن کامل-Glucocerebrosidase activity in mammalian stratum corneum
Although previous studies have demonstrated a crucial role for the enzyme b -glucocerebrosidase (GlcCer’ase) in the final steps of membrane structural maturation in mammalian stratum cornuem (SC) and epidermal homeostasis, the precise in vivo localization of GlcCer’ase activity and protein is not known. Here, we developed a fluorogenic in situ assay on histologic sections (zymography) to elucid...
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ژورنال
عنوان ژورنال: International Journal of Cosmetic Science
سال: 2012
ISSN: 0142-5463,1468-2494
DOI: 10.1111/j.1468-2494.2012.00723.x