Strategies to improve guideline adherence: a randomized clinical trial

Randomized trial of lottery-based incentives to improve warfarin adherence.

BACKGROUND Poor adherence to medications is a major cause of morbidity and inadequate drug effectiveness. Efforts to improve adherence have typically been either ineffective or too complex to implement in clinical practice. Lottery-based incentive interventions could be a scalable approach to improving adherence. METHODS This was a randomized, controlled clinical trial of a daily lottery-base...

Adherence to colorectal cancer screening: a randomized clinical trial of competing strategies.

BACKGROUND Despite evidence that several colorectal cancer (CRC) screening strategies can reduce CRC mortality, screening rates remain low. This study aimed to determine whether the approach by which screening is recommended influences adherence. METHODS We used a cluster randomization design with clinic time block as the unit of randomization. Persons at average risk for development of CRC i...

Strategies to improve drug adherence.

The demographic development of increasing numbers of elderly patients with chronic diseases requiring continuous polypharmacy represents a challenge for medical care. At present, 30–40% of all German patients .65 years are prescribed four or more different medications, and this number is expected to increase. Nonadherence to medical treatments is an increasingly recognized cause of adverse trea...

Pragmatic trial of health care technologies to improve adherence to pediatric asthma treatment: a randomized clinical trial.

IMPORTANCE Most patients with asthma take fewer than half of prescribed doses of controller medication. Interventions to improve adherence have typically been costly, impractical, and at best only minimally successful. OBJECTIVE To test a speech recognition (SR) intervention to improve adherence to pediatric asthma controller medication. DESIGN, SETTING, AND PARTICIPANTS The Breathe Well st...

Does Adding Dexamethasone to Clomiphene Citrate Improve Ovulation in PCOS Patients? A Triple - Blind Randomized Clinical Trial Study