Stored Red Blood Cell Transfusion Induces Regulatory T Cells
نویسندگان
چکیده
منابع مشابه
Red Blood Cell Transfusion Practices
Red blood cell (RBC) transfusion therapy is used in the clinical setting for a variety of indications, including patient resuscitation, augmentation of oxygen delivery, and to reverse or alleviate the symptoms of anemia [1–5]. Despite calls for a more conservative approach to blood transfusion as early as the late 1950s [6,7], the trend toward more cautious transfusion practices did not begin u...
متن کاملCurrent issues relating to the transfusion of stored red blood cells.
The development of blood storage systems allowed donation and transfusion to be separated in time and space. This separation has permitted the regionalization of donor services with subsequent economies of scale and improvements in the quality and availability of blood products. However, the availability of storage raises the question of how long blood products can and should be stored and how ...
متن کاملBiochemical and cellular changes in leukocyte-depleted red blood cells stored for transfusion.
BACKGROUND To evaluate biochemical and cellular changes associated with the storage of leukocyte-depleted red blood cells (RBCs). METHODS We investigated 10 leukocyte-depleted RBC units, randomly chosen from volunteer donors. Every week an aliquot was collected for laboratorial evaluation, which included complete cell blood count, glucose-6-phosphate dehydrogenase (G6PD) activity, extracellul...
متن کاملAutologous transfusion of stored red blood cells increases pulmonary artery pressure.
RATIONALE Transfusion of erythrocytes stored for prolonged periods is associated with increased mortality. Erythrocytes undergo hemolysis during storage and after transfusion. Plasma hemoglobin scavenges endogenous nitric oxide leading to systemic and pulmonary vasoconstriction. OBJECTIVES We hypothesized that transfusion of autologous blood stored for 40 days would increase the pulmonary art...
متن کاملAnemia and red blood cell transfusion
Introduction Red cell transfusion is an extremely common medical intervention. In the United States, more than 16 million red blood cell (RBC) units are transfused annually to 3.4 million patients.Worldwide, 85 million units of blood are collected per year. In Northern England, about 50% of units are given tomedical patients, and 40% to surgical patients; hip replacement and coronary artery byp...
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ژورنال
عنوان ژورنال: Journal of the American College of Surgeons
سال: 2009
ISSN: 1072-7515
DOI: 10.1016/j.jamcollsurg.2008.08.012