Stimulative effect of calcium ions on p-aminohippurate accumulation in rat kidney cortical slices.
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چکیده
منابع مشابه
Renal tubular transport: accumulation of p-aminohippurate by rabbit kidney slices.
I NVESTIGATIONS on the biochemical mechanisms involved in active renal tubular transport are difficult to approach with the various experimental techniques now available. The study of isolated enzyme systems can at best present only a fragmentary picture of a complex physiological process. The clearance technique, while permitting precise measurement of certain tubular activities throws little ...
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نتایج این مطالعه نشان می دهد که مقدار کلسیم (یونیزه و تام)، منیزیم و فسفر به طور معنی داری تغییر پیدا کرد به جزء مقدار کلسیم تام و منیزیم در روش داخل عضلانی که تغییر معنی داری نداشته است. بر اساس نتایج این مطالعه می توان نتیجه گیری کرد که اکسی تتراساکلین بر روی مقادیر سرمی کلسیم و منیزیم تأثیر می گذارد باید مقدار این کاتیون ها در بیماران، در هنگامی که اکسی تتراسایکلین استفاده می شود مورد توجه ق...
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1. The effects of Ca(2+) ions and the nutritional state of the animals on the distribution of soluble protein between the medium, cytoplasmic and particulate fractions after incubation of rat-liver slices have been studied. 2. The Ca(2+)ions decreased the leakage of cytoplasmic protein into the medium and increased the loss of protein from the particles; the effects were more marked with livers...
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In slices of mouse kidney cortex, p-aminohippurate (PAH) is taken up by the organic anion transport system and then rapidly acetylated to p-acetylaminohippurate acid (PAAH), so that there is little net accumulation of PAH itself. The basic characteristics of this system have been described. Uptake may be measured as the total of PAH and PAAH combined. Both uptake and acetylation are dependent o...
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Rat liver mitochondria allowed to accumulate maximal amounts of Ca(++) and HPO(4) (=) ions from the suspending medium in vitro during respiration have a considerably higher specific gravity than normal mitochondria and may be easily separated from the latter by isopycnic centrifugation in density gradients of sucrose or cesium chloride. When the mitochondria are allowed to accumulate less than ...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1980
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)53623-x