Steroidogenic enzyme profile in an androgen-secreting adrenocortical oncocytoma associated with hirsustism
نویسندگان
چکیده
منابع مشابه
Steroidogenic enzyme profile in an androgen-secreting adrenocortical oncocytoma associated with hirsustism
Hirsutism induced by hyperandrogenism can be associated with polycystic ovary syndrome, 21-hydroxylase (OH) deficiency or androgen-secreting tumors, including ovarian and adrenal tumors. Adrenal androgen-secreting tumors are frequently malignant. Adrenal oncocytomas represent rare causes of hyperandrogenism. The aim of the study was to investigate steroidogenic enzyme expression and steroid sec...
متن کاملAndrogen secreting adrenocortical tumours.
BACKGROUND Androgen secreting adrenocortical tumours are rare in children and the determination of their malignant potential can be difficult. OBJECTIVES To assess the presentation, histology, and clinical behaviour of these tumours. SETTING Two tertiary referral centres. STUDY DESIGN Retrospective analysis of children diagnosed with an androgen secreting adrenocortical tumour between 197...
متن کاملGiant adrenal myelolipoma associated with 21-hydroxylase deficiency: unusual association mimicking an androgen-secreting adrenocortical carcinoma.
The objective of this study was to describe a case of giant myelolipoma associated with undiagnosed congenital adrenal hyperplasia (CAH) due to 21-hydroxylase (21OH) deficiency. Five seven year-old male patient referred with abdominal ultrasound revealing a left adrenal mass. Biochemical investigation revealed hyperandrogenism and imaging exams characterized a large heterogeneous left adrenal m...
متن کاملAdrenocortical oncocytoma
Rationale:Adrenocortical oncocytoma is an extremely rare tumor of the adrenal gland. Its diagnostic criteria and biological behavior has not yet reached a consensus. The purpose of this study is to investigate the clinical characteristics of adrenocortical oncocytoma. Patient concerns: The clinical data from 11 cases of adrenocortical oncocytoma were retrospectively analyzed. Five patients foun...
متن کاملTestosterone- and Cortisol-Secreting Adrenocortical Oncocytoma: An Unusual Cause of Hirsutism
Objective. Oncocytomas of the adrenal cortex are usually benign and nonfunctional. They are rarely seen as the cause of hirsutism. Therefore, we aimed to report a case of adrenocortical oncocytoma presenting with hirsutism. Methods. We report a testosterone- and cortisol-secreting adrenal oncocytoma in a 23-year-old female patient presenting with hirsutism. Results. The patient had the complain...
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ژورنال
عنوان ژورنال: Endocrine Connections
سال: 2015
ISSN: 2049-3614
DOI: 10.1530/ec-15-0014e