Stereoselective Pharmacokinetics of Esmolol Enantiomers
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چکیده
منابع مشابه
Stereoselective pharmacokinetics of fluoxetine and norfluoxetine enantiomers in pregnant sheep.
We examined the stereoselective disposition of fluoxetine (FX) and its metabolite norfluoxetine (NFX) in five pregnant sheep. Racemic FX was administered i.v. to the ewe (50 mg) and the fetus (10 mg) on separate occasions. Maternal and fetal blood, maternal urine, and fetal amniotic and tracheal fluid samples were collected for 72 h. FX and NFX isomers were quantified by gas chromatography-mass...
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Theanine, first discovered in tea, is a chiral nonproteinic amino acid that has been reported to have cardiovascular, neurological, and oncological effects. It is being considered as a therapeutic/medicinal agent and additive in consumer products. The present study evaluated the pharmacokinetics of D-theanine, L-theanine, and D,L-theanine in plasma and urine using LC-ESI/MS in rats after oral (...
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ژورنال
عنوان ژورنال: Drug Metabolism and Pharmacokinetics
سال: 2001
ISSN: 0916-1139
DOI: 10.2133/dmpk.16.427