Stereocomplex poly(lactic acid) nanocoated chitosan microparticles for the sustained release of hydrophilic drugs
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چکیده
منابع مشابه
Hydrophilic Natural Polymers for Sustained-controlled Release of Calcium Hydroxide
Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH chan...
متن کاملHydrophilic Natural Polymers for Sustained-controlled Release of Calcium Hydroxide
Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH chan...
متن کاملPreparation and Evaluation of Chitosan-Treated Alginate Microparticles for Sustained Release of All-trans Retinoic Acid
Recently, efforts have been focused on microparticles prepared with natural polymers such as alginates and chitosans. Sodium alginate in particular has been commercially applied and investigated due to its low cost and minimal processing requirements (Murata et al., 1993; Gombotz & Wee, 1998; Sezer & Akbuga, 1999a and b). The use of sodium alginate for microencapsulation has been extensively st...
متن کاملTheophylline-Ethylcellulose Microparticles: Screening of the Process and Formulation Variables for Preparation of Sustained Release Particles
Objective(s) The aim of this study was to formulate and evaluate microencapsulated controlled release preparations of theophylline using ethylcellulose as the retardant material with high entrapment efficiency. Materials and Methods Microspheres were prepared by water-in-oil-in-oil (W/O1/O2) emulsion-solvent diffusion (ESD). A mixed solvent system consisting of acetonitrile and dichloromet...
متن کاملSustained Release of Risedronate from PLGA Microparticles Embedded in Alginate Hydrogel for Treatment of Bony Lesions
Background: Inflammatory bone resorption in periodontitis can lead to tooth loss. Systemic administration of bisphosphonates such as risedronate for preventing bone resorption can cause adverse effects. Alginate hydrogel (ALG) and poly (lactic acid-co-glycolic acid) (PLGA) microparticles have been studied as drug delivery systems for sustained release of drugs. Therefore, the release pattern of...
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ژورنال
عنوان ژورنال: Materials Science and Engineering: C
سال: 2017
ISSN: 0928-4931
DOI: 10.1016/j.msec.2017.03.170