Statistical Modeling of protein spray drying at the lab scale
نویسندگان
چکیده
منابع مشابه
Modeling of Particle Formation during Spray Drying
A mathematical model for the evaporation of a single droplet, subjected to convective drying in a spray dryer was developed to study the transient phenomena of particle formation. During the constant-rate drying period, the governing equations and boundary conditions were transformed into a form containing Peclet number, Pe, as the main controlling parameter. A numerical solution was developed ...
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Purpose Spray drying is a growing technology in the pharmaceutical industry with several enabling applications in modern drug delivery. Its understanding is still vastly empirical, mainly in what relates to the particle formation step. Consequently, the design spaces are typically defined through costly experiments and their statistical interpretation. The purpose of this study is to examine th...
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2002
ISSN: 1530-9932
DOI: 10.1208/pt030104