STAT3 signal transduction through interleukin-22 in oral squamous cell carcinoma

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STAT3 signal transduction through interleukin-22 in oral squamous cell carcinoma

Interleukin (IL)-22 is a member of the IL-10 family. Its main targets are epithelial cells, not immune cells. We examined IL-22 signal transduction in oral squamous cell carcinoma (OSCC) cells. Immunohistochemical staining revealed that IL-22R was expressed more highly in OSCC compared to normal regions. An IL-22R signal was also observed in metas...

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ژورنال

عنوان ژورنال: International Journal of Oncology

سال: 2012

ISSN: 1019-6439,1791-2423

DOI: 10.3892/ijo.2012.1594