STAT1-Deficient Mice Are Resistant to Cecal Ligation and Puncture–Induced Septic Shock
نویسندگان
چکیده
منابع مشابه
Interferon gamma receptor deficient mice are resistant to endotoxic shock
Antibody neutralization studies have established interferon gamma (IFN-gamma) as a critical mediator of endotoxic shock. The advent of IFN-gamma receptor negative (IFN gamma R-/-) mutant mice has enabled a more direct assessment of the role of IFN-gamma in endotoxin (lipopolysaccharide [LPS]-induced shock. We report that IFN gamma R-/- mice have an increased resistance to LPS-induced toxicity, ...
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ژورنال
عنوان ژورنال: Shock
سال: 2012
ISSN: 1073-2322
DOI: 10.1097/shk.0b013e318265a2ab