Standardized mean differences cause funnel plot distortion in publication bias assessments
نویسندگان
چکیده
منابع مشابه
Standardized mean differences cause funnel plot distortion in publication bias assessments
Meta-analyses are increasingly used for synthesis of evidence from biomedical research, and often include an assessment of publication bias based on visual or analytical detection of asymmetry in funnel plots. We studied the influence of different normalisation approaches, sample size and intervention effects on funnel plot asymmetry, using empirical datasets and illustrative simulations. We fo...
متن کاملIn an empirical evaluation of the funnel plot, researchers could not visually identify publication bias.
BACKGROUND AND OBJECTIVE Publication bias and related biases can lead to overly optimistic conclusions in systematic reviews. The funnel plot, which is frequently used to detect such biases, has not yet been subjected to empirical evaluation as a visual tool. We sought to determine whether researchers can correctly identify publication bias from visual inspection of funnel plots in typical-size...
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BACKGROUND Despite efforts to assure high methodological standards, systematic reviews may be affected by publication bias. The objective of this study was to evaluate the occurrence of publication bias in a collection of high quality systematic reviews on reproductive health. METHODS Systematic reviews included in the Reproductive Health Library (RHL), issue No 9, were assessed. Funnel plot ...
متن کاملTrim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis.
We study recently developed nonparametric methods for estimating the number of missing studies that might exist in a meta-analysis and the effect that these studies might have had on its outcome. These are simple rank-based data augmentation techniques, which formalize the use of funnel plots. We show that they provide effective and relatively powerful tests for evaluating the existence of such...
متن کاملAsymmetric funnel plots and publication bias in meta-analyses of diagnostic accuracy.
BACKGROUND Despite the great possibility of publication bias in studies of diagnostic test research, empirical studies about publication bias have mainly focused on studies of treatment effect. METHODS A sample of 28 meta-analyses of diagnostic accuracy was selected from the Database of Abstracts of Reviews of Effectiveness (DARE). Methods used to deal with publication and related biases in t...
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ژورنال
عنوان ژورنال: eLife
سال: 2017
ISSN: 2050-084X
DOI: 10.7554/elife.24260