Stable Patterns of CENH3 Occupancy Through Maize Lineages Containing Genetically Similar Centromeres

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Stable Patterns of CENH3 Occupancy Through Maize Lineages Containing Genetically Similar Centromeres

While the approximate chromosomal position of centromeres has been identified in many species, little is known about the dynamics and diversity of centromere positions within species. Multiple lines of evidence indicate that DNA sequence has little or no impact in specifying centromeres in maize and in most multicellular organisms. Given that epigenetically defined boundaries are expected to be...

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Dynamic epigenetic states of maize centromeres

The centromere is a specialized chromosomal region identified as the major constriction, upon which the kinetochore complex is formed, ensuring accurate chromosome orientation and segregation during cell division. The rapid evolution of centromere DNA sequence and the conserved centromere function are two contradictory aspects of centromere biology. Indeed, the sole presence of genetic sequence...

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Inbreeding drives maize centromere evolution.

Functional centromeres, the chromosomal sites of spindle attachment during cell division, are marked epigenetically by the centromere-specific histone H3 variant cenH3 and typically contain long stretches of centromere-specific tandem DNA repeats (∼1.8 Mb in maize). In 23 inbreds of domesticated maize chosen to represent the genetic diversity of maize germplasm, partial or nearly complete loss ...

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ژورنال

عنوان ژورنال: Genetics

سال: 2015

ISSN: 1943-2631

DOI: 10.1534/genetics.115.177360