Stable expression and characterization of brazzein, thaumatin and miraculin genes related to sweet protein in transgenic lettuce

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Functional expression of the taste-modifying protein, miraculin, in transgenic lettuce.

Taste-modifying proteins are a natural alternative to artificial sweeteners and flavor enhancers and have been used in some cultures for centuries. The taste-modifying protein, miraculin, has the unusual property of being able to modify a sour taste into a sweet taste. Here, we report the use of a plant expression system for the production of miraculin. A synthetic gene encoding miraculin was p...

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Expression of Plant Sweet Protein Brazzein in the Milk of Transgenic Mice

Sugar, the most popular sweetener, is essential in daily food. However, excessive sugar intake has been associated with several lifestyle-related diseases. Finding healthier and more economical alternatives to sugars and artificial sweeteners has received increasing attention to fulfill the growing demand. Brazzein, which comes from the pulp of the edible fruit of the African plant Pentadipland...

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Heterologous Expression of the Secale cereal Thaumatin-Like Protein in Transgenic Canola Plants Enhances Resistance to Stem Rot Disease

Canola (Brassica napus L.) is an important oilseed crop. A serious problem in cultivation of this crop andyield loss, are due to fungal disease stem rot caused by Sclerotinia sclerotiorum. The pathogenesis-related(PR) proteins have the potential for enhancing resistance against fungal pathogen. Thaumatin-like proteins(TLPs) have been shown to have antifungal activity on variou...

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Monkey electrophysiological and human psychophysical responses to mutants of the sweet protein brazzein: delineating brazzein sweetness.

Responses to brazzein, 25 brazzein mutants and two forms of monellin were studied in two types of experiments: electrophysiological recordings from chorda tympani S fibers of the rhesus monkey, Macaca mulatta, and psychophysical experiments. We found that different mutations at position 29 (changing Asp29 to Ala, Lys or Asn) made the molecule significantly sweeter than brazzein, while mutations...

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Brazzein a small, sweet protein: discovery and physiological overview.

For many years, only small molecules were considered capable of inducing a sweet taste (cf. Inglett, 1974). This idea was shattered when miraculin from the miracle fruit of Synsepalum dulcificum was shown to have (Brouwer et al., 1968; Kurihara and Beidler, 1968) a mol. wt of 24 600. The search for sweeteners was no longer limited to small molecules and resulted within a few years in the discov...

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ژورنال

عنوان ژورنال: Journal of Plant Biotechnology

سال: 2018

ISSN: 1229-2818,2384-1397

DOI: 10.5010/jpb.2018.45.3.257