Stability of sumatriptan succinate in polypropylene syringes
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چکیده
منابع مشابه
Stability of cefazolin sodium in polypropylene syringes and polyvinylchloride minibags.
BACKGROUND Cefazolin is a semisynthetic penicillin derivative with a narrow spectrum of activity covering some gram-positive organisms and a few gram-negative aerobic bacteria. OBJECTIVE To determine the physical and chemical stability of cefazolin sodium reconstituted with sterile water for injection and stored in polypropylene syringes or diluted with either 5% dextrose in water (D5W) or 0....
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INTRODUCTION The anti-angiogenic monoclonal antibody, bevacizumab, is currently used by intravitreal administration as off-label drug to treat age-related macular degeneration or other ophthalmologic diseases. For this purpose, commercial bevacizumab is repackaged in 1mL polypropylene syringes under sterile conditions. However, no complete study on the stability of this hospital-based preparati...
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BACKGROUND Pantoprazole sodium, a proton-pump inhibitor, is approved for the short-term treatment of several types of ulcer, Zollinger-Ellison syndrome, and gastroesophageal reflux disease. OBJECTIVE To determine the physical compatibility and chemical stability of ethylenediaminetetra-acetic acid (EDTA)-free pantoprazole in glass vials, polypropylene syringes, and polyvinylchloride (PVC) min...
متن کاملStability-indicating micellar electrokinetic chromatography method for the analysis of sumatriptan succinate in pharmaceutical formulations.
A micellar electrokinetic chromatography method for the determination of sumatriptan succinate in pharmaceutical formulations was developed. The effects of several factors such as pH, surfactant and buffer concentration, applied voltage, capillary temperature, and injection time were investigated. Separation took about 5 min using phenobarbital as internal standard. The separation was carried o...
متن کاملIn vivo bioavailability studies of sumatriptan succinate buccal tablets
UNLABELLED BACK GROUND AND THE PURPOSE OF STUDY: Sumatriptan succinate is a Serotonin 5- HT1 receptor agonist, used in treatment of migraine. It is absorbed rapidly but incompletely when given orally and undergoes first-pass metabolism, resulting in a low absolute bioavailability of about 15%. The aim of this work was to design mucoadhesive bilayered buccal tablets of sumatriptan succinate to ...
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ژورنال
عنوان ژورنال: American Journal of Health-System Pharmacy
سال: 1999
ISSN: 1079-2082,1535-2900
DOI: 10.1093/ajhp/56.10.983