Stability of KcsA Tetramer Depends on Membrane Lateral Pressure
نویسندگان
چکیده
منابع مشابه
The influence of a membrane environment on the structure and stability of a prokaryotic potassium channel, KcsA.
The lack of a membrane environment in membrane protein crystals is considered one of the major limiting factors to fully imply X-ray structural data to explain functional properties of ion channels [Gulbis, J.M. and Doyle, D. (2004) Curr. Opin. Struct. Biol. 14, 440-446]. Here, we provide infrared spectroscopic evidence that the structure and stability of the potassium channel KcsA and its chym...
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ژورنال
عنوان ژورنال: Biochemistry
سال: 2004
ISSN: 0006-2960,1520-4995
DOI: 10.1021/bi036129d