Spontaneous Spinal Cerebrospinal Fluid Leaks and Intracranial Hypotension

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Spontaneous spinal cerebrospinal fluid leaks and intracranial hypotension.

CONTEXT Spontaneous intracranial hypotension is caused by spontaneous spinal cerebrospinal fluid (CSF) leaks and is known for causing orthostatic headaches. It is an important cause of new headaches in young and middle-aged individuals, but initial misdiagnosis is common. OBJECTIVE To summarize existing evidence regarding the epidemiology, pathophysiology, diagnosis, and management of spontan...

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Intracranial hypotension secondary to spontaneous spinal cerebrospinal fluid leaks.

A 37-year-old woman presented with acute orthostatic hypotension and diffuse headache. Brain magnetic resonance imaging (MRI) revealed T2 hyperintense bilateral subdural effusions, diffuse pachymeningeal enhancement, slit ventricles and venous engorgement compatible with spontaneous intracranial hypotension. Single photon emission computed tomography with computed tomography (CT) and CT-cistern...

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Connective tissue disorders with spontaneous spinal cerebrospinal fluid leaks and intracranial hypotension: a prospective study.

OBJECTIVE Intracranial hypotension attributable to a spontaneous spinal cerebrospinal fluid (CSF) leak is an increasingly recognized cause of postural headaches. The cause of these leaks is poorly understood, but it is likely multifactorial and may involve a primary connective tissue disorder. We undertook a study to estimate the contribution of systemic connective tissue disorders to the devel...

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Diagnostic criteria for spontaneous spinal CSF leaks and intracranial hypotension.

BACKGROUND AND PURPOSE Comprehensive diagnostic criteria encompassing the varied clinical and radiographic manifestations of spontaneous intracranial hypotension are not available. Therefore, we propose a new set of diagnostic criteria. MATERIALS AND METHODS The diagnostic criteria are based on results of brain and spine imaging, clinical manifestations, results of lumbar puncture, and respon...

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Spontaneous intracranial hypotension: spinal MR findings.

We report three patients with spontaneous intracranial hypotension in whom spinal MR imaging revealed ventral extradural fluid collections that were centered at the cervicothoracic junction in two patients and extended throughout the entire spine in the third patient. These spinal fluid collections most likely resulted from the accumulation of CSF at the site of dural leakage. Knowledge of this...

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ژورنال

عنوان ژورنال: JAMA

سال: 2006

ISSN: 0098-7484

DOI: 10.1001/jama.295.19.2286