Spontaneous recovery varies inversely with the training-extinction interval

Modeling the Role of Hippocampus in Extinction and Spontaneous Recovery

The ability of animals to learn complex tasks from reward is still not fully understood. While models of such reinforcement learning exist (e.g., Sutton & Barto 1990), it is unclear how these models might reflect the functioning of biological neural networks. One recent model has shown how networks of spiking neurons can model reinforcement learning in animals (Chorley & Seth 2011), however, it...

Inhibition of Spontaneous Recovery of Fear by mGluR5 after Prolonged Extinction Training

Fear behavior is vital for survival and involves learning contingent associations of non-threatening cues with aversive stimuli. In contrast, excessive levels of fear can be maladaptive and lead to anxiety disorders. Generally, extensive sessions of extinction training correlates with reduced spontaneous recovery. The molecular mechanisms underlying the long-term inhibition of fear recovery fol...

Spacing extinction trials alleviates renewal and spontaneous recovery.

Studies of extinction in classical conditioning situations can reveal techniques that maximize the effectiveness of exposure-based behavior therapies. In three experiments, we investigated the effect of varying the intertrial interval during an extinction treatment in a fear-conditioning preparation with rats as subjects. In Experiment 1, we found less fear at test (i.e., more effective extinct...

Extinction and spontaneous recovery of spatial behavior in pigeons.

We investigated extinction and spontaneous recovery of spatial associations using a landmark-based appetitive search task in a touchscreen preparation with pigeons. Four visual landmarks (A, B, C, and D) were separately established as signals of a hidden reinforced target among an 8 × 7 array of potential target locations. The target was located above landmarks (LM) A and C and below B and D. A...

Alcohol Ataxia Tolerance: Extinction Cues, Spontaneous Recovery, and Relapse