Spontaneous Erythroleukemia in a 16-Wk-Old Female Slc:SD Rat

16-year-old female with amenorrhea.

Vasospastic angina in a 16-year-old female.

A 16-year-old female with a family history of coronary artery disease was referred to hospital because of recurrent chest oppression unrelated to exertion. Although a selective coronary angiogram showed no atherosclerotic lesions, coronary spasm was provoked by acetylcholine in the left coronary artery, accompanied by chest pain and depression of blood pressure. This is the youngest healthy you...

Acute Vision Change in a 16-year-old Female

Idiopathic intracranial hypertension (IIH), also known as pseudotumor cerebri, defined as elevated intracranial pressure with no evident cause found on extensive evaluation. Figures 1 and 2 show bilateral papilledema. Headache is absent in some patients with IIH, especially in the pediatric population.1,2 Abducens nerve palsy is a common finding. Oculomotor palsy (as in our case) and other cran...

Spontaneous Mammary Adenocarcinoma in a Twelve-week-old Female Sprague-Dawley Rat

Spontaneous mammary adenocarcinoma was observed in a 12-week-old female SD rat. A movable mass in the right cervical region was found at 11 weeks of age, and the rat was sacrificed the following week. The mass was located in the vicinity of the right salivary gland and measured 38 mm × 26 mm × 16 mm in gross size. It was a firm whitish mass, with a cut surface that was also whitish in appearanc...

Spontaneous Iron Accumulation in Hepatocytes of a 7-Week-Old Female Rat

Spontaneous iron accumulation in hepatocytes was observed in a 7-week-old female Han Wistar GALAS rat. Very fine yellowish brown pigments, which showed a positive reaction with Berlin Blue stain, were apparent in the cytoplasm close to the bile canaliculi, with a diminishing periportal-to-centrilobular gradient. There were also differences in distribution between and within lobes. Transmission ...