Spironolactone is an Effective and Well Tolerated Systemic Antiandrogen Therapy for Hirsute Women*
نویسندگان
چکیده
منابع مشابه
Systemic Inhibition of CREB is Well-tolerated in vivo
cAMP-response element binding protein (CREB) is a nuclear transcription factor activated by multiple extracellular signals including growth factors and hormones. These extracellular cues activate CREB through phosphorylation at Ser133 by various protein serine/threonine kinases. Once phosphorylated, it promotes its association with transcription coactivators CREB-binding protein (CBP) and its p...
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PURPOSE Stereotactic body radiation therapy (SBRT) provides high rates of local control (LC) and margin-negative (R0) resections for locally advanced pancreatic cancer (LAPC) and borderline resectable pancreatic cancer (BRPC), respectively, with minimal toxicity. METHODS AND MATERIALS A single-institution retrospective review was performed for patients with nonmetastatic pancreatic cancer tre...
متن کاملStudy regarding the microscopic aspects of pilo-sebaceous units after antiandrogen treatment in hirsute women.
AIM To analyze the morphological data of pilo-sebaceous units in hirsute women before and 12 months after the antiandrogen treatment with Cyproterone acetate (CPA) 100 mg÷day. MATERIALS AND METHODS Fourteen female patients with idiopathic hirsutism that followed an antiandrogen treatment with CPA were biopsied from the androgen-dependent area of the chin before and 12 months after the treatme...
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INTRODUCTION Acne and hirsutism are common manifestations of hyperandrogenism. AIM To investigate whether or not acne is present in women with hirsutism, associated with different clinical, endocrine and ultrasonographic features. MATERIAL AND METHODS The prospective study included 135 women with hirsutism, aged 14-46 years. We measured the levels of hormones with radioimmunoassay/immunorad...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 1989
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem-68-5-966