Spinal promyelocytic sarcoma as the initial manifestation of acute promyelocytic leukaemia
نویسندگان
چکیده
منابع مشابه
Acute Promyelocytic Leukaemia
Acute promyelocytic leukemia (APL) represents 15 % of acute myeloid leukaemia. Prior to tretinoin usage, the treatment of APL was difficult and remission rates were low especially in developing countries due to mortality resulting primarily from bleeding'. APL is associated with a coagulopathy which may be due to a combination of disseminated intravascular coagulation and primary fibrinolysis. ...
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To cite: Jain A, Lad D, Malhotra P, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016217457 DESCRIPTION Examination of the oral cavity provides valuable clues to a large number of systemic disorders. Gum hypertrophy is usually associated with myelomonocytic and monocytic subtypes of acute myeloid leukaemia. Its occurrence in a case of acute promyelocytic...
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Acute promyelocytic leukaemia (APML) is a subtype of leukaemia arising from a distinct reciprocal translocation involving chromosomes 15 and 17, which results in the PML-RARA fusion gene. Over the past three decades, APML has been transformed from a highly fatal disease to a highly curable one. This drastic improvement is because of the introduction of a new treatment strategy with all-trans re...
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Acute promyelocytic leukaemia (APL) is characterised by proliferation of abnormal promyelocytes. The reciprocal translocation between the long arms of chromosomes 15 and 17, and the fusion between the retinoic acid receptor (RARa) gene, and PML gene, is unique to APL. Because of unsuccessful cytogenetic analysis of conventional G-banding technique (mitoses were not observed), we diagnosed three...
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Acute non-lymphocytic leukaemia is a well recognised and increasingly reported complication of treated Hodgkin's disease. The prognosis is generally poor with a disappointing response to chemotherapy. A patient in whom myelodysplastic features appeared after treatment for Hodgkin's disease, to be followed shortly afterwards by acute promyelocytic leukaemia, is reported. Complete remission was a...
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ژورنال
عنوان ژورنال: Neurología (English Edition)
سال: 2018
ISSN: 2173-5808
DOI: 10.1016/j.nrleng.2017.02.007