Spinal cord protection with intravenous nimodipine
نویسندگان
چکیده
منابع مشابه
Effect of nimodipine on rat spinal cord injury.
We evaluated the potentially protective effect of nimodipine on rat spinal cord injury. Sprague-Dawley rats received spinal cord injury, and were separated into nimodipine (N = 12) and saline groups (N = 12). Within 1 h of the injury, rats were treated intraperitoneally with nimodipine (1.0 mg/kg) or an equal amount of saline. Treatment was performed 3 times a day for 1 week. Operation BBB scor...
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Background & Aim: Spinal cord injury (SCI) has a very long history, and its cases form a large proportion of patients admitted to trauma centers in Iran. Studies show that repair after spinal cord injury can be done. In fact, many pharmaceutical agents, such as erythropoietin (EPO), are applied to reduce secondary injury following the initial disorder and to maintain the nerve tissue. Methods &...
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Five minutes before spina! cord injury. an 0.02 mg/kg dese of nimodipine was started via a femora! catheter and continued for 96 hours after injury. Pre-and post-injury and post-infusion mean arterla! blood pressure (MABP)recordings were obtained. The levels of injured cord sodium-potassium-adenosine triphosphatase activity were measured. There was a statistical!y significant decrease in MABP a...
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The mortality and morbidity of extensive thoracoabdominal aorta replacement has improved markedly in recent years [1]. However, postoperative paraplegia from spinal cord infarction remains the most devastating complication that faces patients undergoing surgery on the thoracoabdominal aorta because loss of lowerlimb function imposes severe constraints on the quality of life. Additionally, parap...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1992
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)34697-5