Spinal Cord Injury: Pathophysiology, Multimolecular Interactions, and Underlying Recovery Mechanisms
نویسندگان
چکیده
منابع مشابه
Instrumental learning within the spinal cord: underlying mechanisms and implications for recovery after injury.
Using spinally transected rats, research has shown that neurons within the L4-S2 spinal cord are sensitive to response-outcome (instrumental) relations. This learning depends on a form of N-methyl-D-aspartate (NMDA)-mediated plasticity. Instrumental training enables subsequent learning, and this effect has been linked to the expression of brain-derived neurotrophic factor. Rats given uncontroll...
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متن کامل[Pathophysiology of acute spinal cord injury].
Spinal cord injury is one of the most devastating of all traumatic conditions that can be encountered by patients. Over the past years much research has been performed on elucidating the mechanisms of spinal cord injury. Experimental and clinical studies have suggested that acute spinal cord injury is a two-step process involving primary and secondary mechanisms. Primary injury of the spinal co...
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Introduction: The present systematic review and meta-analysis aims to conduct a comprehensive and complete search of electronic resources to investigate the role of administrating Chondroitinase ABC (ChABC) in improving complications following Spinal Cord Injuries (SCI). Methods: MEDLINE, Embase, Scopus, and Web of Sciences databases were searched until the end of 2019. Two independent reviewe...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms21207533