Sperm pathology: a step beyond descriptive morphology. Origin, characterization and fertility potential of abnormal sperm phenotypes in infertile men

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Sperm pathology: a step beyond descriptive morphology. Origin, characterization and fertility potential of abnormal sperm phenotypes in infertile men.

Sperm pathology is presented as the discipline of characterizing structural and functional deficiencies in abnormal spermatozoa. This concept complements that of sperm morphology mainly concerned with the appearance of spermatozoa. These two notions collaborate in providing correlations of prognostic value with sperm fertilizing capacity, explaining the mechanisms of sperm inefficiency, suggest...

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Correlation of sperm morphology and oxidative stress in infertile men

Background: Excess reactive oxygen species (ROS) in the semen is believed to affect fertility in men. Morphologically abnormal sperms and their relation to seminal oxidative stress in infertile and subfertile men are not clear. Objective: To correlate various sperm morphological defects with seminal oxidative stress in infertile and subfertile men. Materials and Methods: The study included 25 p...

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Sperm morphology, motility, and concentration in fertile and infertile men.

BACKGROUND Although semen analysis is routinely used to evaluate the male partner in infertile couples, sperm measurements that discriminate between fertile and infertile men are not well defined. METHODS We evaluated two semen specimens from each of the male partners in 765 infertile couples and 696 fertile couples at nine sites. The female partners in the infertile couples had normal result...

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Correlation between sperm ultrastructure in infertile patients with abnormal sperm morphology and DNA damage.

This study explored the correlation between sperm ultrastructure in infertile patients with abnormal sperm morphology and DNA damage. Three unusual sperm morphologies were selected for the experimental group namely case 1 (95% headless sperm), case 2 (98% headless sperm), and case 3 (100% headless sperm), and the control group consisted of 2 subjects (20 and 15% headless sperm). For case 1, the...

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correlation of sperm morphology and oxidative stress in infertile men

background: excess reactive oxygen species (ros) in the semen is believed to affect fertility in men. morphologically abnormal sperms and their relation to seminal oxidative stress in infertile and subfertile men are not clear. objective: to correlate various sperm morphological defects with seminal oxidative stress in infertile and subfertile men. materials and methods: the study included 25 p...

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ژورنال

عنوان ژورنال: Human Reproduction Update

سال: 2003

ISSN: 1355-4786,1460-2369

DOI: 10.1093/humupd/dmg034