Spectroscopic tools for an automated suspension cell culture screening system
نویسندگان
چکیده
منابع مشابه
Development of an automated, multiwell plate based screening system for suspension cell culture
Introduction The automation of cell culture processes becomes more important in the pharmaceutical industry due to compressed timelines and the need to develop more products more efficiently. This drive to develop new processes faster and more efficient requires a streamlined workflow. Resource intensive approaches like the use of shake flasks limit the accessible design space for the developme...
متن کاملDevelopment and application of an automated, multiwell plate based screening system for suspension cell culture
Introduction The already presented automated, multiwell plate (MWP) based screening system for suspension cell culture is now routinely used in process development. It is characterized by a fully automated workflow with integrated analytical instrumentation and uses shaken 6-24 well plates as bioreactors which can be run in batch and fed-batch mode with a capacity of up to 384 reactors in paral...
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An automated suspension culture system for the cultivation of Plasmodium falciparum is described which retains a degree of flexibility which is absent in other automated culture apparatuses. Not only does this system of cultivation promote rapid multiplication of asexual parasites but also permits the development and maturation of gametocytes. Using a combination of gelatin flotation and N-acet...
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There is increasing demand for automated and quantitative cell culture technology, driven both by the intense activity in stem cell biology and by the emergence of systems biology. We built a fully automated cell culture screening system based on a microfluidic chip that creates arbitrary culture media formulations in 96 independent culture chambers and maintains cell viability for weeks. Indiv...
متن کاملSeed train optimization for suspension cell culture
Introduction The purpose of a seed train is the generation of an adequate number of cells for the inoculation of a production bioreactor. This is timeand cost-intensive: From volumes used for cell thawing or cell line maintenance the cell number has to be increased. The cells are usually run through many cultivation systems which become larger with each passage (e.g. T-flasks, roller bottles or...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2015
ISSN: 1753-6561
DOI: 10.1186/1753-6561-9-s9-p31