Spectroscopic Photoacoustic Molecular Imaging of Breast Cancer using a B7-H3-targeted ICG Contrast Agent
نویسندگان
چکیده
منابع مشابه
Spectroscopic Photoacoustic Molecular Imaging of Breast Cancer using a B7-H3-targeted ICG Contrast Agent
Purpose: Breast cancer imaging methods lack diagnostic accuracy, in particular for patients with dense breast tissue, and improved techniques are critically needed. The purpose of this study was to evaluate antibody-indocyanine green (ICG) conjugates, which undergo dynamic absorption spectrum shifts after cellular endocytosis and degradation, and spectroscopic photoacoustic (sPA) imaging to dif...
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There is an urgent need for sensitive and specific tools to accurately image early stage, organ-confined human prostate cancers to facilitate active surveillance and reduce unnecessary treatment. Recently, we developed an acoustic lens that enhances the sensitivity of photoacoustic imaging. Here, we report the use of this device in conjunction with two molecular imaging agents that specifically...
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Our preliminary photoacoustic data indicates that we could detect small objects (tubes with a cross-section of 1mm) containing 100 micro moles of contrast agent up to about 5cm in the breast-tissue like environment. For the case of 10 micro moles concentration of the dye, we could detect such small objects up to about 3cm. This depth can be increased further (by at least another 2cm) by the use...
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ژورنال
عنوان ژورنال: Theranostics
سال: 2017
ISSN: 1838-7640
DOI: 10.7150/thno.18217