Spectrophotometric method for analysis of metformin hydrochloride
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منابع مشابه
Selective Spectrophotometric Determination of Metformin Hydrochloride in Pharmaceuticals and Urine Using Two Nitrophenols as Chromogenic Agents
Metformin hydrochloride (MFH) is an oral anti-diabetic drug of biguanide class. Two selective spectrophotometric methods were presented for the determination of MFH in pharmaceuticals. The methods were based on the measurement of yellow-coloured charge-transfer complexes formed between MFH and two poly-nitrophenols, namely, 2,4-dinitrophenol (DNP method, at 405 nm) and picric acid (PA met...
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Simple, accurate and precise Zero order, first derivative spectrophotometric and chromatographic methods have been developed and validated for the determination of linagliptin (LNG) and metformin HCl (MET). The zero order and first derivative spectrophotometric methods were used for the determination of LNG in the range of 5-30 μg mL(-1) by measuring the absorbance at 299 nm and 311 respectivel...
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A new spectrophotometric method for the estimation of tamsulosin hydrochloride in pharmaceutical dosage forms has been developed and validated. The method is based on reaction between drug and bromophenol blue and complex was measured at 421 nm. The slope, intercept and correlation coefficient was found to be 0.054, -0.020 and 0.999, respectively. Method was validated in terms of specificity, l...
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INTRODUCTION Labetalol HCl is a selective α1 and non-selective β adrenergic blocker used to treat high blood pressure. Chemically it is 2-hydroxy-5-{[1-hydroxy-2-(4 phenyl butane -2-lyl) amino]ethyl}benzamide. It has a molecular formula of C19H24N2O3.Hcl and a molecular weight of 328.40 g/mol and its structure was given in Figure No. 1. Literature survey revealed, few analytical methods which i...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2009
ISSN: 0250-474X
DOI: 10.4103/0250-474x.51947