SPECIFICITY OF ANTI-GLOBULIN FACTORS IN HUMAN SERA
نویسندگان
چکیده
منابع مشابه
Properties of Various Anti-γ-globulin Factors in Human Sera
The serological and physicochemical properties of the following three forms of human anti-gamma-globulin factors were compared: (a) rheumatoid factors; (b) Milgrom type anti-gamma-globulin factors; and (c) factors directed against an antigen in human gammaG-globulin that is hidden in the intact molecule and revealed by enzymatic digestion at low pH. The property common to these factors is abili...
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Abstract Background: Lymphoproliferative disorders are among the most serious and potentially fatal complications of chronic immunosuppression in kidney transplant recipients. The principle risk factors for development of PTLD are the degree of overall immunosuppression and the EBV serostatus of the recipient. In this study, the risk of PTLD in kidney transplant recipients who received Anti- L...
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The m a j o r i t y o f n o r m a l h u m a n se ra h e m o l y z e sheep e r y t h r o c y t e s in the p r e s e n c e o f c o m p l e m e n t ( "hemoly zers") , w h e r e a s s e ra o f the r e m a i n i n g populat ion do not lyze sheep e r y t h r o e y t e s C~nonhemolyzers") . The antibodies respons ib le for this lyt ic ac t iv i ty a r e n o w identified as be ing specific to F o r s s...
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Rheumatoid factors in the sera of patients with rheumatoid arthritis appear to be specifically directed against genetically determined "antigens" in human gamma-globulin. At least eight rheumatoid factors of differing specificity exist; usually several are present in combination in the same serum. The different rheumatoid factors can be readily detected through their pattern of reactivity with ...
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I N PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) accelerated destruction of abnormal red cells occurs within an apparently benign extracorpuscular environment.1 Although the underlying cellular defect has not yet been fully elucidated, it has long been recognized that, in vitro, PNII erythrocytes are extraordinarily susceptible to immune lysis. The possibility exists that, in vivo, destruction of ...
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ژورنال
عنوان ژورنال: Journal of the Japan Society of Blood Transfusion
سال: 1975
ISSN: 1883-8383,0546-1448
DOI: 10.3925/jjtc1958.21.81