Specific oral tolerance induction in food allergy
نویسندگان
چکیده
منابع مشابه
Specific oral tolerance induction in food allergy.
Specific oral tolerance in food allergy can be induced by oral administration of the offending food, starting with very low dosages, gradually increasing the daily dosage up to an amount equivalent to a usually relevant dose for daily intake, followed up by a daily maintenance dose. Unfortunately, the body of scientific evidence concerning specific oral tolerance induction (SOTI) is still rathe...
متن کاملSpecific oral tolerance induction in food allergy in children: efficacy and clinical patterns of reaction.
BACKGROUND Specific oral tolerance induction (SOTI) seems to be a promising treatment of food allergy. Specific oral tolerance induction and elimination diet were compared with respect to efficacy rate and patterns of clinical reaction. METHODS Children with challenge proven immunoglobulin E (IgE)-mediated cow's milk (CM) allergy or hen's egg (HE) allergy were randomly assigned to SOTI or eli...
متن کاملSpecific Oral Tolerance Induction in Food Allergy in Children: Efficacy and Clinical Patterns of Reaction
who underwent OFCs at the Duke University pediatric allergy-immunology clinic, excluding patients with a history of severe symptoms with previous reactions, were studied. Patient-selection criteria were based on the clinical history, results of skin-prick tests, and foodspecific immunoglobulin E (IgE) levels that were much lower than those previously published levels predictive of a high likeli...
متن کاملDual specific oral tolerance induction using interferon gamma for IgE-mediated anaphylactic food allergy and the dissociation of local skin allergy and systemic oral allergy: tolerance or desensitization?
BACKGROUND Specific oral tolerance induction (SOTI) for IgE-mediated food allergy (IFA) can be successfully achieved using interfero gamma (classic SOTI). OBJECTIVE In this study, a tolerable dose was introduced during tolerance induction with interferon gamma (dual SOTI), and its effectiveness was evaluated. METHODS The study population comprised 25 IFA patients. Blood samples were taken f...
متن کاملSpecific oral tolerance induction for food. A systematic review.
BACKGROUND Specific oral tolerance induction (SOTI) is a new therapeutic approach in the treatment of persistent food allergy. OBJECTIVE The purpose of this article is to systematically review the literature in order to identify, appraise, and synthesize the evidence about SOTI efficacy and safety. METHODS A comprehensive search for citations was conducted on May 2, 2009 using MEDLINE via P...
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ژورنال
عنوان ژورنال: Allergy
سال: 2006
ISSN: 0105-4538,1398-9995
DOI: 10.1111/j.1398-9995.2006.01066.x