Species-specific variations in H1 histone phosphopeptides.

Specific interaction of histone H1 with eukaryotic DNA.

The interaction of calf thymus histone H1 with homologous and heterologous DNA has been studied at different ionic strengths. It has been found that about 0.5 M NaCl histone H1, and its fragments N-H1 (residues 1-72) and C-H1 (residues 73-C terminal), precipitate selectively a small fraction of calf thymus DNA. This selective precipitation is preserved up to very high values (less than 2.0) of ...

Hormone-mediated dephosphorylation of specific histone H1 isoforms.

We have previously shown a connection between histone H1 phosphorylation and the transcriptional competence of the hormone inducible mouse mammary tumor virus (MMTV) promoter. Prolonged exposure of mouse cells to dexamethasone concurrently dephosphorylated histone H1 and rendered the MMTV promoter refractory to hormonal stimulation and, therefore, transcriptionally unresponsive. Using electrosp...

Sequence specific binding of chlamydial histone H1-like protein.

Chlamydia trachomatis is one of the few prokaryotic organisms known to contain proteins that bear homology to eukaryotic histone H1. Changes in macromolecular conformation of DNA mediated by the histone H1-like protein (Hc1) appear to regulate stage specific differentiation. We have developed a cross-linking immunoprecipitation protocol to examine in vivo protein-DNA interaction by immune preci...

Variations of Ertyhrocyte Histone H1 Subtypes in a Muscovy Duck Population

Multiple non-allelic subtypes of histone H1 have been detected in higher organisms. These specific variants with distinct structural features may differ in their ability to condense chromatin and hence modify transcriptional activity. Such functional divergence between H1 subtypes has still not been established definitively, but it cannot be excluded that the role of a particular subtype may de...

Nucleosome in Complex with Linker Histone H1