Spatiotemporal patterns of macrophage migration inhibitory factor (Mif) expression in the mouse placenta
نویسندگان
چکیده
منابع مشابه
Spatiotemporal patterns of macrophage migration inhibitory factor (Mif) expression in the mouse placenta
BACKGROUND Macrophage migration inhibitory factor (MIF) has special pro-inflammatory roles, affecting the functions of macrophages and lymphocytes and counter-regulating the effects of glucocorticoids on the immune response. The conspicuous expression of MIF during human implantation and early embryonic development also suggests this factor acts in reproductive functions. The overall goal of th...
متن کاملI-43: Expression Profile of Macrophage Migration Inhibitory Factor (MIF) Signaling Pathway as A Potentional Biomarker in Pathophysiology of Endometriosis
Background MIF via its receptor, CD74, initiates a signaling cascade that leads to proliferation and survival of cells. Also, MIF binding to CD74 activates p38 signaling pathways that lead to positive effect on the expression of COX-2. The aim of this study was to evaluate the gene expression profile of MIF, CD74 and COX-2 in normal, ectopic and eutopic endometrium during menstrual cycle. The e...
متن کاملO-28: Endometriosis Is Influenced by The Promoter Haplotype-Based Expression of Macrophage Migration Inhibitory Factor (MIF)
Background: Macrophage migration inhibitory factor (MIF) is a key pro-inflammatory cytokine that is secreted by accumulated active macrophages in ectopic tissue of endometriosis. MIF is involved in pathophysiological events of endometriosis, such as angiogenesis and cell proliferation. MIF that stimulates the synthesis of PGE2, leads to over-expression of local estradiol synthesis in endometrio...
متن کاملCorrelation between urine macrophage migration inhibitory factor (MIF)/creatinine ratio and time after kidney transplantation
Abstract Background: Despite the long-standing association of macrophage migration inhibitory factor (MIF) with delayed-type hypersensitivity response, the potential role of MIF in chronic allograft nephropathy is unknown. The association between upregulation of MIF expression, macrophage and T cell infiltration and the severity of chronic allograft nephropathy suggests that MIF may be an ...
متن کاملMacrophage migration inhibitory factor (MIF), a role in COPD
Authors: 5 Gunnar R. Husebø, Per S. Bakke, Rune Grønseth, Jon A. Hardie, Thor Ueland, Pål 6 Aukrust, Tomas M.L. Eagan. 7 8 Dept. of Thoracic Medicine, Haukeland University Hospital, Bergen Norway 9 2 Dept. of Clinical Science, University of Bergen, Norway 10 Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway 11 K.G. Jebsen Inflammatory Research Centre...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Reproductive Biology and Endocrinology
سال: 2010
ISSN: 1477-7827
DOI: 10.1186/1477-7827-8-95