Spatial Distribution of PEO–PPO–PEO Block Copolymer and PEO Homopolymer in Lipid Bilayers
نویسندگان
چکیده
منابع مشابه
Preparation, Characterization and Pharmacodynamic Evaluation of Fused Dispersions of Simvastatin using PEO-PPO Block Copolymer
The solubility enhancement of poorly soluble compounds is an important task in pharmaceutical technology as it leads to better bioavailability and a more efficient application. Fused dispersions (FDs) of simvastatin (SIM) using PEO-PPO block copolymer were prepared which paved the way for the formation of an amorphous product with enhanced dissolution and bioavailability. The accumulative s...
متن کاملPreparation, Characterization and Pharmacodynamic Evaluation of Fused Dispersions of Simvastatin using PEO-PPO Block Copolymer
The solubility enhancement of poorly soluble compounds is an important task in pharmaceutical technology as it leads to better bioavailability and a more efficient application. Fused dispersions (FDs) of simvastatin (SIM) using PEO-PPO block copolymer were prepared which paved the way for the formation of an amorphous product with enhanced dissolution and bioavailability. The accumulative s...
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The order-order transition temperature (T(OOT)) in blends of poly(styrene-b-isoprene-b-styrene) (S-I-S) triblock copolymer and polyisoprene (PI) homopolymer was investigated by using synchrotron small-angle X-ray scattering (SAXS). Pure triblock copolymer undergoes an order-order transition (OOT) from hexagonally ordered cylinder (HEX) to body centered cubic (BCC) phases. In order to investigat...
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Numerous previous studies have established that the addition of a microphase-ordered AB diblock copolymer to a thin homopolymer A (hA) film can slow, if not altogether prevent, film rupture and subsequent film dewetting on a hard substrate such as silica. However, only a few reports have examined comparable phenomena when the hA/AB blend resides on a soft B-selective surface, such as homopolyme...
متن کاملStability of monolayers and bilayers in a copolymer-homopolymer blend model
We study the stability of layered structures in a variational model for diblock copolymerhomopolymer blends with respect to perturbations of their interfaces. The main step consists of calculating the first and second derivatives of a sharp-interface Ohta–Kawasaki energy for straight monoand bilayers and determining the sign of the latter. By developing the interface perturbations in a Fourier ...
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ژورنال
عنوان ژورنال: Langmuir
سال: 2020
ISSN: 0743-7463,1520-5827
DOI: 10.1021/acs.langmuir.9b03208