منابع مشابه
Spatial control of exocytosis.
During many key biological processes, exocytosis is confined to distinct regions of the plasma membrane. Spatial control of exocytosis correlates with altered membrane skeleton dynamics and assembly of local membrane microdomains. These domains act as local stages for the assembly and the regulation of molecular complexes (targeting patches) that mediate vesicle-membrane fusion. Furthermore, lo...
متن کاملSpatial Regulation of Exocytosis: Lessons from Yeast
M any types of cells maintain specialized plasma membrane domains to which different subsets of secretory vesicles are targeted, enabling the cells’ performance of specific functions. The budding yeast Saccharomyces cerevisiae spatially and temporally regulates exocytosis, directing surface growth and secretion to different plasma membrane sites at different cell cycle stages (21). In very smal...
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15 صفحه اولControl of granule exocytosis in neutrophils.
Neutrophils are granulocytes derived from bone marrow that circulate through the blood and become recruited to tissues during infection or inflammation. They are the most abundant white blood cell and comprise the first line of defence in the innate immune system. However, they are also capable of causing tissue damage in a wide range of diseases. Release of chemotactic signals from inflamed or...
متن کاملSNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis.
Lipid rafts are microdomains present within membranes of most cell types. These membrane microdomains, which are enriched in cholesterol and glycosphingolipids, have been implicated in the regulation of certain signal transduction and membrane traffic pathways. To investigate the possibility that lipid rafts organize exocytotic pathways in neuroendocrine cells, we examined the association of pr...
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ژورنال
عنوان ژورنال: Current Opinion in Cell Biology
سال: 2003
ISSN: 0955-0674
DOI: 10.1016/s0955-0674(03)00074-7