Space-Time Cluster Analysis of Invasive Meningococcal Disease

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Space-Time Cluster Analysis of Invasive Meningococcal Disease

Clusters are recognized when meningococcal cases of the same phenotypic strain (markers: serogroup, serotype, and subtype) occur in spatial and temporal proximity. The incidence of such clusters was compared to the incidence that would be expected by chance by using space-time nearest-neighbor analysis of 4,887 confirmed invasive meningococcal cases identified in the 9-year surveillance period ...

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Web - based Supplementary Materials for “ A space - time conditional intensity model for invasive meningococcal disease occurence ”

Sebastian Meyer1,2, Johannes Elias3, and Michael Höhle4,2 1Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität, München, Germany 2Department of Statistics, Ludwig-Maximilians-Universität, München, Germany 3German Reference Centre for Meningococci, University of Würzburg, Würzburg, Germany 4Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany

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A space-time conditional intensity model for invasive meningococcal disease occurrence.

A novel point process model continuous in space-time is proposed for quantifying the transmission dynamics of the two most common meningococcal antigenic sequence types observed in Germany 2002-2008. Modeling is based on the conditional intensity function (CIF), which is described by a superposition of additive and multiplicative components. As an epidemiological interesting finding, spread beh...

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ژورنال

عنوان ژورنال: Emerging Infectious Diseases

سال: 2004

ISSN: 1080-6040,1080-6059

DOI: 10.3201/eid1009.030992