SP-0369: Radiobiology of combined therapies

Combined Therapies in Abdominal Actinomycosis

CAMELIA VIDITA GURBAN1, FLORINA-MARIA ANDRICA2*, COSMIN CITU3, ELENA HOGEA3*, IOSIF MARINCU4, MARIOARA CORNIANU5, OVIDIU ALEXANDRU MEDERLE6 1 Victor Babes University of Medicine and Pharmacy Timisoara, Department of Biochemistry and Pharmacology, 2 Eftimie Murgu Sq., 300041, Timisoara, Romania 2 Victor Babes University of Medicine and Pharmacy Timisoara, Department of Pharmaceutical Chemistry ,...

Proton Radiobiology

In addition to the physical advantages (Bragg peak), the use of charged particles in cancer therapy can be associated with distinct biological effects compared to X-rays. While heavy ions (densely ionizing radiation) are known to have an energy- and charge-dependent increased Relative Biological Effectiveness (RBE), protons should not be very different from sparsely ionizing photons. A slightly...

Radiobiology of Radioresistant Glioblastoma

Therapy of glioblastoma has been very problematic with disappointing results using multiple therapeutic approaches. In general, glioblastomas are considered radioresistant tumors with different radiation modalities failing to control them in the clinic. However a comprehensive and detailed analysis of the radiosensitivity of glioblastoma cells has not been performed. We now present such an anal...

Radiobiology of tissue reactions.

Tissue effects of radiation exposure are observed in virtually all normal tissues, with interactions when several organs are involved. Early reactions occur in turnover tissues, where proliferative impairment results in hypoplasia; late reactions, based on combined parenchymal, vascular, and connective tissue changes, result in loss of function within the exposed volume; consequential late effe...

Handbook of Radiobiology