SP-0208: Radiotherapy of Hodgkin Lymphoma: Revolutionary Roots, Challenging Present, Bright Horizons

Radiotherapy for Hodgkin Lymphoma

Hodgkin Lymphoma and Anaplastic Variants of Non-Hodgkin Lymphoma

  Background and Objectives: Classic Hodgkin lymphoma (CHL), anaplastic large cell lymphoma (ALCL) and some cases of diffuse large B cell lymphoma (DLBCL) have overlapping morphologic features. Since they all represent distinct clinico-pathologic entities, we explored the differential diagnostic impact of immunophenotyping to discriminate between them. Materials and Methods:...

XVII. Radiotherapy in early stage Hodgkin lymphoma.

The treatment of patients with Hodgkin lymphoma (HL) is one of the major success stories in oncology and 60–90% of patients are cured of their malignancy depending on clinical stage and risk factors. Radiotherapy was used to cure patients with HL as early as the 1940s, but more widespread successes came in the 1960s for early stage diseases I A and II A with the use of extended field radiothera...

Secondary malignancy after radiotherapy for Hodgkin Lymphoma

Hodgkin lymphoma (HL), formerly called Hodgkin disease, has attained high survival rates (≥75% at ten years for all grades and stages combined, age-standardised), with continued improvements in treatment modalities since the 1940s, when radiotherapy was first used to combat the disease. Today, sequential chemotherapy and radiation are used in many cases, but certain groups of patients, dependen...

Histologic subtypes of breast cancer following radiotherapy for Hodgkin lymphoma.

BACKGROUND The purpose of the study was to determine whether breast cancers (BCs) that develop in women previously irradiated for Hodgkin lymphoma (HL) are biologically similar to sporadic BC. MATERIALS AND METHODS We retrospectively reviewed the charts of patients who developed BC after radiotherapy (RT) for HL. Tumors were classified as ductal carcinoma in situ (DCIS) or invasive carcinoma....