Some Concerns About Diagnostic Test Accuracy for Infections

Studies of diagnostic test accuracy

Definition of a diagnostic test accuracy study? o A diagnostic test accuracy study evaluates the accuracy of index test in correctly distinguishing between those with disease and those without disease compared to gold standard test. o Gold standard test is also called criterion test or reference test. o For a diagnostic test to be accurate, it should be both valid (accuracy) and reliable (preci...

Cochrane diagnostic test accuracy reviews

In 1996, shortly after the founding of The Cochrane Collaboration, leading figures in test evaluation research established a Methods Group to focus on the relatively new and rapidly evolving methods for the systematic review of studies of diagnostic tests. Seven years later, the Collaboration decided it was time to develop a publication format and methodology for Diagnostic Test Accuracy (DTA) ...

Some Concerns About Newborn Screening for Congenital Hypothyroidism in China

Meta-analysis of Diagnostic Test Accuracy Studies

Interactive visualisation for interpreting diagnostic test accuracy study results

Information about the performance of diagnostic tests is typically presented in the form of measures of test accuracy such as sensitivity and specificity. These measures may be difficult to translate directly into decisions about patient treatment, for which information presented in the form of probabilities of disease after a positive or a negative test result may be more useful. These probabi...